Brian F. Degenhardt, Nissar A. Darmani, Jane C. Johnson, Lex C. Towns, Diana C. J. Rhodes, Chung Trinh, Bryan McClanahan, and Vincenzo DiMarzo
J Am Osteopath Assoc 2007 107:387-400.
[Abstract]
[Full Text]
[PDF]
The effects of osteopathic manipulative treatment were studied in a
prospective, blinded assessment that analyzed pre- and posttreatment serum
levels of {beta}-endorphin, serotonin, 5-hydroxyindoleacetic acid, anandamide,
and N-palmitoylethanolamide in a sample of 20 subjects. The degree and
duration of changes to these circulatory pain biomarkers were greater in
subjects with chronic low back pain than in control subjects without that
disorder.