Eric S. Felber
J Am Osteopath Assoc 2006 106:609-614.
[Abstract]
[Full Text]
[PDF]
Clostridium botulinum is a gram-positive anaerobic bacterium that
produces a very potent neurotoxin, causing muscle paralysis. The author
discusses the biochemical mechanisms by which botulinum toxin type A can be
used in the primary care setting to treat allergic rhinitis, hyperhidrosis,
lichen simplex, migraine, myofascial pain syndrome, and certain task-specific
idiopathic focal dystonias. The action of botulinum toxin type A on
acetylcholine in the autonomic nervous system as well as its antispasmodic
properties make the toxin a clinically useful agent in the management of many
conditions.