HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Vijayaraghavan, K. Articles by Mitzel, H. M. Search for Related Content PubMed PubMed Citation Articles by Vijayaraghavan, K. Articles by Mitzel, H. M.

Krishnaswami Vijayaraghavan, MD^*; Michelle L. Jeffries, MS; Mara L. Windsor, BS; Anne M. Yost, BS; Bridget Stiegler, BS; Ned L. Williams, DO; Heather M. Mitzel, BA

Purpose: Metabolic syndrome (MS) constitutes a cluster of risk factors for cardiovascular disease such as hypertriglyceridemia, hypertension, diabetes, central obesity, and low high-density lipoprotein levels. Any three of the above risk factors qualifies to be classified as MS. Many patients undergoing cardiovascular surgical and percutaneous interventions may not have been diagnosed and treated adequately for this syndrome so as to prevent perioperative morbidity. The prevalence of MS and postoperative complications has not been described adequately in the literature.

Methods: All patients undergoing cardiovascular and thoracic surgery and percutaneous interventions at a specialty hospital over a 12-month period between June 2001 and June 2002 were included in the study.

Data were collected on demographics, risk factors, laboratory data and diagnostics preoperatively and type of intervention and postoperative complications. Patients were classified as having MS with at least 3 or 4 or 5 risk factors. Analysis was performed using SPSS version 12.0.

Results: Of the 312 patients, 68.6% were males and 31.4% females. MS was prevalent in 54.4% of patients with 33.3% having 3 risk factors, 14.4% having 4 risk factors, and 6.7% having all 5 risk factors. Most frequent interventions were percutaneous coronary interventions (27%), endoluminal graft of aorta (16%), peripheral arterial interventions (15%), coronary artery bypass surgery (14%), abdominal aneurysm repair (11%), carotid endartectomy (10%), and femoral popliteal bypass surgery (5%).

Most common postoperative complications include renal dysfunction (20%), blood transfusion requirement (17%), pleuropericardial effusion (12%), atrial fibrillation (7.4%), congestive heart failure (2%), and stroke (2%). Overall prevalence of complications was 42%.

Conclusions: (1) Prevalence of MS is high in patients admitted to hospital for cardiothoracic and vascular surgical or percutaneous interventions. (2) Prevalence of postoperative complications is high in this high-risk interventional procedure.

Clinical Implications: An opportunity exists to identify patients with MS preoperatively in cardiothoracic and vascular interventions (both surgical and percutaneously) and implement preventive therapeutic strategies to decrease postoperative morbidity and mortality.

^* Arizona Heart Hospital and Institute, Phoenix; Midwestern University's Arizona College of Osteopathic Medicine, Glendale.

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Vijayaraghavan, K. Articles by Mitzel, H. M. Search for Related Content PubMed PubMed Citation Articles by Vijayaraghavan, K. Articles by Mitzel, H. M.