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Journal of the American Osteopathic Association, Vol 99, 7 Suppl, 1S-1S
Copyright © 1999 by American Osteopathic Association

Articles

Leukotriene modifiers in the management of asthma

MH Elnabtity, RF Singh, MA Ansong, and TJ Craig

Leukotrienes play a major role in the underlying pathophysiology of asthma. Leukotriene-receptor antagonists and direct leukotriene-synthesis inhibitors may be important new agents in maintenance therapy for asthma. Their role may also extend to attenuating exercise-induced and allergen-induced bronchospasm. This article reviews the effectiveness of available leukotriene modifiers in various clinical studies, reviews their adverse effects profile, and discusses their potential roles in the management of asthma.





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Copyright © 1999 by the American Osteopathic Association.