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Journal of the American Osteopathic Association, Vol 96, Issue 7, 419-419
Copyright © 1996 by American Osteopathic Association

Case Reports

Metaplastic breast carcinoma

DM Smith, VA Rongaus, TW Wehmann, PJ Agarwal, and GJ Classen

Metaplastic breast carcinoma, a rare entity, accounts for only about 0.02% of all breast carcinomas. It involves the transformation of mammary neoplasms into osteoid and chondroid substances. Because of the relatively small patient population and the limited number of controlled studies, there is confusion regarding its classification and staging. Its histogenesis is unknown. The authors describe a 65-year-old woman with findings consistent with metaplastic breast carcinoma. Theories as to etiology and prognosis as well as treatment are discussed.


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O. W. Petersen, H. L. Nielsen, T. Gudjonsson, R. Villadsen, F. Rank, E. Niebuhr, M. J. Bissell, and L. Ronnov-Jessen
Epithelial to Mesenchymal Transition in Human Breast Cancer Can Provide a Nonmalignant Stroma
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Copyright © 1996 by the American Osteopathic Association.