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Journal of the American Osteopathic Association, Vol 92, Issue 7, 907-907
Copyright © 1992 by American Osteopathic Association

Articles

Therapeutic drug monitoring: lithium levels

NB Coffman and JJ Fernandes

Lithium has been used in the treatment of mania since 1949. Although its effectiveness is well recognized, the mechanism by which it stabilizes manic behavior is not well understood. In addition, it has some serious toxic properties combined with a narrow therapeutic range. For this reason, monitoring of serum lithium levels is mandatory. Suggested mechanisms of action and protocols for monitoring of serum levels are presented.




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Copyright © 1992 by the American Osteopathic Association.