As the HIV epidemic spreads, throughout the United States, and as an increasing number of persons become infected with the virus and manifest its many complications, more and more physicians are being asked to give presentations on HIV disease to professional and community groups. This is especially true since AIDS education has become a primary prevention tool. The author provides guidelines for giving a talk on AIDS. The general principles are applicable to presentations both to other health professionals and to lay-community groups. The outline can be varied, and the lecture material can be expanded or summarized to meet the needs of the particular audience. Sources for further information are also provided.