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Dr Galluzzi is on the speakers bureau for Eisai Inc.

Address correspondence to Katherine E. Galluzzi, DO, CMD, Department of Geriatrics, Philadelphia College of Osteopathic Medicine, 4190 City Ave, Rowland Hall, Suite 315, Philadelphia, PA 19131-1633. E-mail: katherineg{at}pcom.edu

Treatment strategies for herpes zoster infection include limiting viral replication with anti-infective agents as well as limiting associated acute and chronic neuropathic pain with a variety of analgesics. The author outlines currently available pharmacotherapeutic options, from first-line (eg, anti-infective agents, tricyclic antidepressants, anticonvulsants, opioid analgesics, and topical agents) through adjuvant treatments (eg, oral corticosteroids). A summary of adverse event profiles is provided for each medication. Vaccination is recommended as a preventive measure.