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Dr Pharo is currently in private practice in Philadelphia, Pa, with Professional Pain Management Associates; he was previously affliliated with Jefferson Medical College and Jefferson Pain Center, where Dr Zhou is assistant professor of physical medicine and rehabilitation and anesthesiology, and an attending physician, Dr Pharo is on the speakers bureau of Pfizer Inc. Dr Zhou has no commercial, proprietary, or financial interest in the products discussed in this article

Address correspondence to Gregory H. Pharo, DO, PPMA, Suite 308, 829 Spruce St, Philadelphia, PA 19107.E-mail: gregory.pharo{at}ppmapc.com

Cancer remains the second most common cause of death in the United States despite advances in prevention, early detection, and newer treatment protocols. Pain continues to be the most feared complication of this diagnosis. Numerous studies have shown that when the World Health Organization treatment guidelines are followed, 90% of patients are pain-free. Although clinical evidence is convincing that opioids are effective in treating patients for cancer pain, physician reluctance to prescribe them and patient unwillingness to take such medication continue. Barriers to opioid use are multifactorial, but with education of healthcare providers and patients, pharmacotherapy for pain management will be more effective.