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Dr Pertusi is on the speakers bureau and is a consultant for Merck & Co and Pfizer Inc. He has conducted research and has received grant support from both of these companies.

Correspondence to Raymond M. Pertusi, DO, Associate Professor of Medicine, Division of Rheumatology, Department of Internal Medicine, University of North Texas Health Science Center at Fort Worth—Texas College of Osteopathic Medicine, 855 Montgomery St, Fort Worth, TX 76107-2553. E-mail: rpertusi{at}hsc.unt.edu

Traditional nonsteroidal anti-inflammatory drugs are contraindicated for surgical or short-term posttraumatic analgesia. Selective cyclooxygenase inhibitors (coxibs) do not inhibit platelets and can be used in these settings. Coxibs reduce sensitization of the nervous system. The use of coxibs as part of a multimodal analgesia results in a reduction in the amount of opioids needed to control pain. Reduced opioid toxicity may hasten recovery.